Books written or edited by our associates

 

 
Developmental and Reproductive Toxicology, a Practical Approach, Second Edition
Edited by Ronald D. Hood
List Price: $199.95
Cat. #: 1254
SBN: 084931254X
Publication Date: 8/30/2005
Number of Pages: 1168
 
 CRC Press

Developmental and reproductive toxicology are increasingly important areas of interest, encompassing the study of toxicant effects on development, from conception through sexual maturity, and the ability of mature adults to successfully reproduce. The importance of these areas was evidenced by the formation of the Center for the Evaluation of Risks to Human Reproduction under purview of the National Toxicology Program (NTP) and the National Institute of Environmental Health Sciences. Developmental and Reproductive Toxicology, a Practical Approach, provides a practical guide for developmental and reproductive toxicologists. It is intended for use by individuals working in industry who are responsible for testing chemical agents for developmental and reproductive toxicity or who oversee such endeavors. It is also intended for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. And it will be useful for training students and technicians and for anyone who must become familiar with the included areas of toxicology.

 Previous books, with the exception of the Handbook of Developmental Toxicology, the current book’s predecessor, have largely been “academically oriented” and not intended to guide the practicing developmental or reproductive toxicologist. Conversely, the book is useful as well as informative. It provides insights gained from hands-on experience, in addition to a theoretical foundation. This book also gathers information in one reference that is typically scattered throughout the literature, including comparative developmental milestones, an updated glossary of descriptive terms used in developmental toxicity evaluation, and both U.S. and international regulatory guidelines. 

 

 

 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Handbook of Developmental Toxicology, a Practical Approach
Edited by Ronald D. Hood

Extensive descriptions of how to conduct and evaluate studies in developmental toxicology-valuable advice and theoretical and regulatory bases for studies ranging from safety evaluation to molecular biology to epidemiology are presented by experienced investigators

  • Guidance on statistical analysis and modeling of data-how to evaluate and interpret data, including behavioral data
  • Comparative tables of developmental milestones and reproductive and placental parameters-complete data for humans, rats, mice, rabbits, hamsters, guinea pigs, rhesus monkeys, and chickens
  • Glossary of terms used in developmental toxicity evaluations-promotes consistency, accuracy, and efficiency in data communication and interpretation
  • Composite tables of historical control data from developmental toxicity evaluations of rats and rabbits-provides background incidence data for the standard reproductive parameters evaluated in toxicity tests and for developmental defects
  • 101 equations, 98 figures, 105 tables-illustrations and tabular material make it easy to understand the concepts presented in the text
Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation.
This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.
(Handbook of Developmental toxicology is out of print, but copies may be available from sellers of used books.)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Reproductive Toxicology
 Edited by Raphael J. Witorsch
 ISBN: 0781702259
 Publisher: Taylor and Francis
 Publish Date: 01 October, 1994
 Binding: Hardcover , 2 edition
 Weight: 1.35 pounds
 List Price: USD 149.95
 
Presents not only the major principles and current issues in the field but also provides a physiologic basis for the actions and reactions to reproductive toxic agents. The volume is divided into three sections. The first focuses on the current concepts of normal mammalian reproductive function from the systems to subcellular level. The second explains how toxic substances disrupt the normal functioning of elements of the mammalian reproductive system. The third section discusses other issues of long-standing or recent interest to the field, such as clinical aspects, epidemiology, and the toxic effects of low-energy electromagnetic fields and tobacco, alcohol, and other substances of abuse.  

 


 

 
  
Developmental Toxicology:  Risk Assessment and the Future
Edited by Ronald D. Hood
 ISBN: 0442004222
 Publisher: Van Nostrand Reinhold
 Publish Date: 01 April, 1990
 Binding: Hardcover
 List Price: USD 81.95
 
This book is an outgrowth of the Guidelines for the Health Assessment of Suspect Developmental Toxicants.  In that document, several general areas of research were identified that were needed to fill data gaps or to reduce uncertainties associated with estimating risks for human developmental effects due to exposure to hazardous substances.  Developmental Toxicology, Risk Assessment and the Future focuses on the research needs for risk assessment indicated in the Guidelines, and includes an update and review of each area.  Each chapter focuses on the specific issues within a particular area that hold promise in addressing uncertainties for risk assessment and regulatory decision-making.  A comprehensive listing of relevant literature is included.
[Developmental Toxicology: Risk Assessment and the Future, is out of print.  However, an alternative edition, published by the NTIS for the U.S. Environmental Protection Agency, Office of Health and Environmental Assessment, remains available from the NTIS in three formats  (photocopied pages, CD, or microfiche), as NTIS Order Number PB92-184993.]

 

 

 

 

 

 

 

 

 

Cacodylic Acid: Agricultural Uses, Biologic Effects, and Environmental Fate
by Ronald D. Hood

Publisher: U.S. Government Printing Office
Publish Date: December, 1985
Binding: Paperback

In December 1985, VA published a technical monograph to provide a single source of information on cacodylic acid (CA) and its sodium salt (NaCA). A very limited supply of the 164-page book is still available. University libraries, researchers, and scientists interested in receiving a complimentary copy should write to the Environmental Agents Service (116A), VA Central Office, 810 Vermont Avenue, NW, Washington, DC20420.

Cacodylic acid and its sodium salt were the active ingredients in Agent Blue, one of the group of herbicides used in Vietnam to defoliate hiding places, supply lines, and staging areas held by opposing forces. Along with phenoxy herbicides, Agent Blue was used experimentally in the early to mid-1960's and more extensively from 1965 to 1970. As with the phenoxy herbicides, these organic arsenicals had been widely used in agriculture and forestry for many years with no known risk to human health. The first five chapters focus on the very complex and highly technical aspects of the chemical and physical properties as well as the production, agricultural uses, and environmental considerations of cacodylic acid and its sodium salt. Chapters six through eight discuss pharmacology and toxicology issues, and the ninth (and final chapter) provided a summary overview and describes areas where additional research was needed.